Kathryn M Eisenmann Selected Research

Actins (F Actin)

3/2019	Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
1/2018	Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).
1/2017	mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions.
11/2015	Small-molecule agonists of mammalian Diaphanous-related (mDia) formins reveal an effective glioblastoma anti-invasion strategy.
1/2014	An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.
1/2012	Dia-interacting protein (DIP) imposes migratory plasticity in mDia2-dependent tumor cells in three-dimensional matrices.

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Kathryn M Eisenmann Research Topics

Disease

10	Neoplasms (Cancer) 01/2022 - 12/2003
3	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 11/2015
2	Neoplasm Metastasis (Metastasis) 01/2018 - 01/2017
2	Ovarian Neoplasms (Ovarian Cancer) 03/2016 - 01/2014
1	Glioma (Gliomas) 03/2019
1	Margins of Excision 03/2019
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Wounds and Injuries (Trauma) 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Lung Neoplasms (Lung Cancer) 01/2017
1	Blister (Bulla) 01/2017
1	Inflammation (Inflammations) 03/2015
1	Insulin Resistance 03/2015
1	Wiskott-Aldrich Syndrome 01/2005
1	Melanoma (Melanoma, Malignant) 12/2003

Drug/Important Bio-Agent (IBA)

9	ForminsIBA 01/2022 - 01/2005
6	Actins (F Actin)IBA 03/2019 - 01/2012
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 12/2003
3	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 01/2018 - 01/2012
2	TubulinIBA 03/2019 - 01/2018
2	ChemokinesIBA 01/2018 - 01/2017
2	GTP Phosphohydrolases (GTPases)IBA 01/2014 - 01/2005
1	rho-Associated KinasesIBA 01/2022
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 03/2019
1	CytokinesIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Silybin (Lagosa)IBA 01/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018
1	Conditioned Culture MediaIBA 01/2018
1	CXCR4 Receptors (CXCR4 Receptor)IBA 01/2017
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 03/2015
1	Insulin (Novolin)FDA Link 03/2015
1	Small Interfering RNA (siRNA)IBA 03/2015
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 03/2015
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2003
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 12/2003
1	Alanine (L-Alanine)FDA Link 12/2003
1	Mitogen-Activated Protein KinasesIBA 12/2003
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 12/2003

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2018 - 11/2015
2	Therapeutics 03/2019 - 01/2017
2	Radiotherapy 01/2017 - 11/2015